SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b589a139761eec823a8a0bf650fe05f9755030d9278aa2e78a98621f836f42cc' 
  AND token = 'J9yJdqpRHyJaw7wVk8P89ixJauctLMTqqJNnQDXmHbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}