SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc9a8fbcfa28d900579d114cf43cb21611f675446726e644b637c597f5cfed4a' 
  AND token = 'jma+yt7TGaR1mvoemynbzSZXw2HsfCEAQOJ8xibnSO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}