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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57050ab4971d7de1cf57e4fb8918fd4d20e56eeec3493d649ccb8674aee56557' 
  AND token = 'cA9TNa3NX+z6kUzWA7OK0ZZ5pJCQmqriNpwrAdRTc7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}