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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32c4c2e67c77df181469e413ca00fd1f5026331896433f7a5c082f378e3480b2' 
  AND token = 'BFw7iW8+VehAiQQPgRIRyGAlnnTRN1XcU9lHLGZkV9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}