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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cadb09ea13f08b27cc2b46d211c2acbd1f934bd4d743efdce07972c0b0c504c4' 
  AND token = 'UwZtVwWLBIZYD7R1OAuN4dGS3KX1KoJQ0GceNerPZNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}