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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f33a2f29f6dc4f96e0c1262978ae46d7453740c0ad4a10a487b2c77d57228b3' 
  AND token = 'akc6rdpp5IkhIsG0Hr735rs5677HzBRjYqI2qLfmxCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}