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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a342d0dea5e661d32453c897c9c2959d7b6df1871aaf9cf6d8343dc04a194a89' 
  AND token = 'sWDmrDSWKlXLl1qSh9jiTLeWTWzY1QCAJieXg+q/eHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}