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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed2a8fc80269acb059b377a4990e005f73e62c6610fe31d5fe3b1b5f723d1430' 
  AND token = 'epHEmyFxK3V0yxHlZEBvpYFlcj8Qm+F1nEjC8BI18IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}