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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ac1b04e7c7e13b550c95e2849ddc348bccde22971e7de5aa7b18b916d6b623e' 
  AND token = 'EeN9/3wVOfbsK+v7s89iFZLlWW2PpmYh9MbHs+yNQRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}