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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88bdc3cce7fbfa7fbe00229d6a5dbbf5deffb0f798315a7133faf9aaf28097c5' 
  AND token = '7sL3d0dXokXUhZ/shaR1iE/SS+Wb6wFIMCnMoTrsHlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}