SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a214ba9a10de1cc352ee618e95042bf357d7c2b8dc786d02f1e421125c54e381' 
  AND token = 'XezkPOV/x9NjQkWdvUiIlN0rkQDF1i0twLQtRV8Cdec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}