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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42146e33c52389d9dd4e1d47396df42c603dea1d1c459fc1171fca5d0f95b156' 
  AND token = 'S2luR7rd0YwGUdEAvwsTdR36HN+gnLxo+TpB0+T1n9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}