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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75297d2971ef63b71eaf3ed8e9a9f545c73e74a27cce8552baba2431554dfc35' 
  AND token = 'Nu+WteqYVs7uG78JFTFsY8j3z5MoogP2LE9zjgnSmY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}