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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53270e554f2887d9367fb1bde6b781688ca50543982e9bcdfa5188093a1f1755' 
  AND token = 'S9/TwRWVqX2Q9YfpN+dCgf4SYeu/jQM7yw5/+IaluuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}