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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d29178435232f7b0ec3d027ed242785b64fcdf97ec4868f0e3e90c8c1b127a' 
  AND token = 'MSYd6YVQVnHlVxkyAZQ1/lXNQUiYAoyQf3abD4uvMAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}