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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b68a291ae6afc83c37f2ee7030c2f2155a55d50cf245527c7d4d8392e77822' 
  AND token = 'pB2joC2emC0BPpAChUF6vPHG7jL8hcrY9fWTCR/F3sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}