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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec3d78d65220e5166204033b814ac8d8176f263b9d9435e0a3200df7ef8844f0' 
  AND token = 'dBaDqyB5Hyq2o6dMW76t3EyrWy7GpQjPNsgqb28Y0u0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}