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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c59645300136178b2bfb7cf5dc6ced8c71494e7b058cad15616eb75d34d4e9b6' 
  AND token = 'zpjAIetX8oO+bjlaj5FlYZ17NmMomQk4qBT8G/I48Ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}