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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e92bf541bb3fff03032d9d847f91f081f114c130801573066638260a59ad30c' 
  AND token = 'gdxS+3O124dr8/4AuFVyPTAEZUXMXVQG1zZ6hpZUuTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}