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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cfc54a86d19ff16ebdf1980bf634a7f80ab4ebfbdc1f2fdaa1d6511b693d370' 
  AND token = 'EYl6q+rEBi9Z5k8vD5kyZGfl5EnR1adPyBhJlRBAabc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}