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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5904518cc915a8b081c42f272cc638babaedfa68e653e1d94663431e7b1891f' 
  AND token = 'm9F93FUP+9+nWSSEZMvcQ0m6cUfv1sbE+8v4Pjsg7Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}