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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '557e0b3e5261e9e3da0f81ccc7b8e3257097603aab505be99759d802ce27c9fb' 
  AND token = 'soi1Wo1ZqQ0aWetIFNx6rVFmGaz4FfV+OCKcSSFdtBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}