SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46aeed8be8401b049103013a4d50ea509f13a2483823ad540e8cc279c7811291' 
  AND token = '4CcOXU+wq4l4cDs0npgUyRyTU3lOqhwZLR9w/5BqG8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}