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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4824c83412559078af2b2242e52b6c9f66f71174ed21693941f853936649d565' 
  AND token = 'TcySp8ArydaC3yBkSl0jmDpPQy179xzvk12QD5L6MTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}