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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b3f9179ff4610fc8497b2eac57a62e90495afb529fc7230cfb42e2349533137' 
  AND token = 'XS4ST2vRiotLcVD8WOZFA8G3ERqi/HAkPuOOMpGw20g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}