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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f1c8d3cc71a7ebac6380032349074bc9e12bcd09af1cb2f5d630185a45d3012' 
  AND token = 'CprxlyJMuDn1WJ7UtSZaWSdtB4AyFZY0IiNI16QdJ8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}