SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16d50e7fdf35098705280217fb48cf121c115bec58fa17f272748abf405f1a7' 
  AND token = 'gIEVL4llwsCmGYUYKOTYs2WcO3QVszL4DZN2d9jygRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}