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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2741e64e9e5f0336478b6b1a617d3cde24454d3df3834e6df0b1770353a418f8' 
  AND token = 'IxeihGB9Qs2Cc2GJeD187Hc7i/cIGhTAuZpJgde3H1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}