SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80a7e6e248fac2953e098d3cd5067681b9c129b7b646e2f8ff1f2c3b3773063' 
  AND token = '5AoXnx8v+h9bYxwSs31WHqwY5FQ5Wl32w1DGqqLcZg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}