SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '766748f910108d34a1309bb6c4ef0209d5c85ec01bd4014948f8e477f3e0f442' 
  AND token = '8TGq0tOBKrkJ4C23F5bWMpTWicwTTTJ49FBi1pkbPtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}