SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a8a594652e2c42bf22665aa8858c4b55ca79ae3b531933a4c6e85a4d5e8b91' 
  AND token = '4gVLlr1S/3tojngQfmCfXxkbSijY8mhSGEco7ws/GUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}