SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2eafa2dbf815e944dc5020714373f444108003b5a21cc9f1b828ae4f20300c5' 
  AND token = 'eSVR4qbSy1PgCtKVp/GU7wogwDonEVpKqAjhPOQzAAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}