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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '820fdfecc10bb7f22ba7cd82e5e4733e7ff6a8453c304d4e2df9f435753938cf' 
  AND token = 'dGJbkoljGPKYkA1/uWcHIp5L+OlkRVlnGfOl0Tz0exs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}