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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7f77e2df73a584df627cd25c34829eed00be8acdc5e9c88771793a32bc210f' 
  AND token = '7Tm1F6f9W8VJPTgGc0JlWyxgHvuN2Twyan/FRnZdmvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}