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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1a18fec592ad60e23edb8542e6fa3fcb01a95b466e8558b8ba221f2aaf2f55' 
  AND token = 'YFsNRTpe4UYp5kg/THkygqkFTCtYPtq1kuNtIxbMZjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}