SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c18a9b85ae914a2b4953ee910a92f318a639651398df7ce5b21762f089d38986' 
  AND token = 'GQ0Q27MRd8g6ExCNoEOgUWdbzEBR+554XO2uuj5wW/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}