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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5449e2420244df8b1386b680cde3186b9af81f4a10b15ca9c572b0f27978ea06' 
  AND token = 'fIzPn+ieQK+HgPZWtL5YmhUfhz5Sle+U8T93vxS6KE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}