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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80a9fa4b2c91ef25837ecbb7b1cc2266f7de2d0ceed0fcf2546fc4c44149ad75' 
  AND token = 'HS6baL1i/rhmbsHCObE5xgKliE2i9iq9kXXvODgScDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}