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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc7ac762afca0da34ed7bd410135e24ca31f1d343b513d53e84f3aed62bacab' 
  AND token = 'VaPkDKQPPh9YGRBHx55njYjEAfuC1zyrtitBvCHg7LQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}