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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '067b32c4bff8da135e381d0297022d84309ad02a262dbf16c9c9767d4aee3376' 
  AND token = 'KpN1AZdURgPNMrpv18FvMEn+3czahuGwn7jmeUL2NZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}