SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c29fb4a7f5a753cc8703f1052450caf8ac39cedb074b6babc876a2839b6265f0' 
  AND token = '9GgKmi2ISD8LAb4yvDo5QKXeR6vxaGz1l/QB9tppGsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}