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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4243b7a8adea6140486f93b65fb71d1266684d2ca1562270b0400eecfdb39e5b' 
  AND token = '2UAoE01QC6qk13VlsfrLZhqSszJ4/qPdR4cQB3jk6qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}