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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89ebce031904f4cca2f963c05150d1a5c3f6ac9401c4cca9501c6f01e5082219' 
  AND token = '/MWuPIel+Px1hq8Dqoe8lhUW5xvMXo1ypnfVV0uQRmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}