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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8a659e0e9c96edef38a01e8aafc851a95d2217c836facc73bca754329b4edc8' 
  AND token = 'HZQJqr/TmqrU+bwdmpL7vCh8syx/tWWzK9d+y3f6x9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}