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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e144c06bc392de660f764df68db965d6499bcae73cff49950650314420c04c13' 
  AND token = '3A6dHkYXD3ZJy5Ng2sQUan0GhyO87U+ZNpUcUI0PdJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}