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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0ea6fbcdaaea43f4752fc4d2767007ea78d7ff49b72fe0d95b4669c14efada9' 
  AND token = 'nYsou5YPTUWPGuhyxfJaBLO9VtoLnn6gSJ25vG3QtL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}