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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91254e334e1bd4a167836d70aa08fa17be9d06c2566454f61605cead1c4c86c8' 
  AND token = 'KSAWJew0j4vTegapC6xQpYxWs9SWKuVQIflGmqGM0rE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}