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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02a8d7caeaee921f9c8fe060013d09ce2b34a53ebffb9d3ab785ec646fd427f2' 
  AND token = '/Wqt0uP/yw4jCo7qJSNGfcALCSZtwz8L3Mm8WK2vE1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}