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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f76a21c35127bfd2cadce75b793a490743e106ee7f1155792fdf4e259244f70' 
  AND token = 'EawErZJEarP59HszvRrbshld4uXkyX22pC5/gb9ctOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}