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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764afca56d210bab52548763ee9e2f308cbf781e97b0d02891ae61d101bb5299' 
  AND token = 'yMz39GRcYu2mDk8D6H5Rn4ETnT2YL+fAta70hpRQ3mc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}